Gocovri (Amantadine) XR Patient Information

Find out why Gocovri is prescribed, side effects of Gocovri, Gocovri warnings and more - in plain English.

Gocovri (goh-KUV-ree)

This is only a brief summary of important information about GOCOVRI and does not replace talking to your doctor about your condition and your treatment.

Gocovri (amantadine) XR Full Prescribing Information

About Gocovri

GOCOVRI is a prescription medicine used for treating dyskinesia (sudden uncontrolled movements) in Parkinson’s disease patients treated with levodopa therapy, with or without other medicines that increase the effects of dopamine in the brain.

It is not known if GOCOVRI is safe and effective in children.

Do not take GOCOVRI if you have severe kidney problems

What to Avoid While Taking Gocovri

  • Do not drive, operate machinery, or do other dangerous activities until you know how GOCOVRI affects you
  • Do not drink alcohol while taking GOCOVRI. It can increase your chances of getting serious side effects

Before Taking Gocovri

Tell your doctor about all of your medical conditions, including if you

  • have kidney problems
  • have daytime or unpredictable sleepiness, or take a medicine to help you sleep or that makes you drowsy
  • have mental problems, such as suicidal thoughts, depression, or hallucinations
  • have unusual urges including gambling, increased sex drive, compulsive eating, or compulsive shopping
  • drink alcohol

Tell your doctor about all the medicines you take. Keep a list that includes all prescription and over-the-counter medicines, vitamins, and herbal supplements you take and show it to your doctor.

Especially tell your doctor if you

  • take medicines like sodium bicarbonate
  • have had or are planning to have a live flu (influenza) vaccination (nasal spray). You can receive the flu shot but should not get a live flu nasal spray vaccination while taking GOCOVRI

How to Take Gocovri

  • Take GOCOVRI exactly as your doctor tells you to
  • Start GOCOVRI with 1 capsule at bedtime. Your doctor may change your dose if needed. If your doctor tells you to take 2 capsules, take them together at bedtime
  • Do not stop or change GOCOVRI before talking with your doctor. Call your doctor if you have symptoms of withdrawal such as fever, confusion, or severe muscle stiffness
  • GOCOVRI may be taken with food or without food
  • Swallow GOCOVRI capsules whole. Do not crush, chew, or divide
  • GOCOVRI capsules may be opened and sprinkled on applesauce before swallowing. Take all of it right away
  • If you miss a dose of GOCOVRI, do not take an extra dose. Take your usual dose of GOCOVRI on the next day at bedtime
  • If you have forgotten to take GOCOVRI for several days, contact your doctor
  • If you take too much GOCOVRI, call your doctor or go to the nearest hospital emergency room right away

Possible Side-Effects of Gocovri

GOCOVRI may cause serious side effects, including

  • falling asleep during normal activities. You may fall asleep while doing normal activities such as driving a car, talking, or eating while taking GOCOVRI or other medicines that treat Parkinson’s disease. You may fall asleep without being drowsy or without warning. This may result in having accidents. Your chances of falling asleep while doing normal activities while taking GOCOVRI are greater if you take other medicines that cause drowsiness. 
  • suicidal thoughts or actions and depression. Some people taking GOCOVRI have had suicidal thoughts, attempted suicide, or depression. 
  • hallucinations. GOCOVRI can cause or worsen hallucinations (seeing or hearing things that are not real) or psychotic behavior. 
  • feeling dizzy, faint or light-headed, especially when you stand up (orthostatic hypotension). Lightheadedness or fainting may happen when getting up too quickly from a sitting or lying position, especially after long periods of time, when first starting GOCOVRI, or if your dose has been increased. 
  • unusual urges. Some people taking GOCOVRI get urges to behave in a way unusual for them, which may include an unusual urge to gamble, increased sexual urges, strong urges to spend money, binge eating, and the inability to control these urges

Contact your doctor right away if you experience any of these side effects.

The most common side effects of GOCOVRI include hallucination, dizziness, dry mouth, swelling of legs and feet, constipation, and falls.

These are not all the possible side effects of GOCOVRI. Tell your doctor if you have any new symptoms while taking GOCOVRI.

Get More Information

This is only a brief summary of important information about GOCOVRI. Talk to your doctor or pharmacist to learn more.

  • For more information about GOCOVRI, go to or call 1-844-GOCOVRI
  • To learn about potential savings, visit or call 1-844-GOCOVRI

Gocovri (amantadine) XR Full Prescribing Information

Gocovri, the Gocovri logo, Gocovri Onboard, Adamas, and the Adamas logo are trademarks of Adamas Pharmaceuticals, Inc. or its related companies. © 2018 Adamas Pharmaceuticals, Inc. or its related companies. All rights reserved. GOC-0147 01/18

APA Reference
Holly, K. (2019, January 22). Gocovri (Amantadine) XR Patient Information, HealthyPlace. Retrieved on 2024, June 13 from

Last Updated: January 22, 2019

Medically reviewed by Harry Croft, MD

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